Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate

BACKGROUND: The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One is amb...

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Detalles Bibliográficos
Autores principales: Liu, Xuejun, Shi, Xinxin, Chen, Chunlin, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609108/
https://www.ncbi.nlm.nih.gov/pubmed/26475308
http://dx.doi.org/10.1186/s12859-015-0750-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609108/
https://www.ncbi.nlm.nih.gov/pubmed/26475308
http://dx.doi.org/10.1186/s12859-015-0750-6

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