Cargando…
Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate
BACKGROUND: The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One is amb...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609108/ https://www.ncbi.nlm.nih.gov/pubmed/26475308 http://dx.doi.org/10.1186/s12859-015-0750-6 |