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CD14(+) macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide

BACKGROUND: Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the role of these cells in HIV infection, a disease fuelled by intestinal inflammat...

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Detalles Bibliográficos
Autores principales: Cassol, Edana, Rossouw, Theresa, Malfeld, Susan, Mahasha, Phetole, Slavik, Tomas, Seebregts, Chris, Bond, Robert, du Plessis, Johannie, Janssen, Carl, Roskams, Tania, Nevens, Frederik, Alfano, Massimo, Poli, Guido, van der Merwe, Schalk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609115/
https://www.ncbi.nlm.nih.gov/pubmed/26475133
http://dx.doi.org/10.1186/s12879-015-1176-5