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CD14(+) macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide
BACKGROUND: Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the role of these cells in HIV infection, a disease fuelled by intestinal inflammat...
Autores principales: | Cassol, Edana, Rossouw, Theresa, Malfeld, Susan, Mahasha, Phetole, Slavik, Tomas, Seebregts, Chris, Bond, Robert, du Plessis, Johannie, Janssen, Carl, Roskams, Tania, Nevens, Frederik, Alfano, Massimo, Poli, Guido, van der Merwe, Schalk W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609115/ https://www.ncbi.nlm.nih.gov/pubmed/26475133 http://dx.doi.org/10.1186/s12879-015-1176-5 |
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