P38 MAPK expression and activation predicts failure of response to CHOP in patients with Diffuse Large B-Cell Lymphoma

BACKGROUND: The p38 MAPK is constitutively activated in B-NHL cell lines and regulates chemoresistance. Accordingly, we hypothesized that activated p38 MAPK may be associated with the in vivo unresponsiveness to chemotherapy in B-NHL patients. METHODS: Tissue microarrays generated from eighty untrea...

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Detalles Bibliográficos
Autores principales: Vega, Gabriel G., Avilés-Salas, Alejandro, Chalapud, J. Ramón, Martinez-Paniagua, Melisa, Pelayo, Rosana, Mayani, Héctor, Hernandez-Pando, Rogelio, Martinez-Maza, Otoniel, Huerta-Yepez, Sara, Bonavida, Benjamin, Vega, Mario I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609122/
https://www.ncbi.nlm.nih.gov/pubmed/26475474
http://dx.doi.org/10.1186/s12885-015-1778-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609122/
https://www.ncbi.nlm.nih.gov/pubmed/26475474
http://dx.doi.org/10.1186/s12885-015-1778-8

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