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P38 MAPK expression and activation predicts failure of response to CHOP in patients with Diffuse Large B-Cell Lymphoma
BACKGROUND: The p38 MAPK is constitutively activated in B-NHL cell lines and regulates chemoresistance. Accordingly, we hypothesized that activated p38 MAPK may be associated with the in vivo unresponsiveness to chemotherapy in B-NHL patients. METHODS: Tissue microarrays generated from eighty untrea...
Autores principales: | Vega, Gabriel G., Avilés-Salas, Alejandro, Chalapud, J. Ramón, Martinez-Paniagua, Melisa, Pelayo, Rosana, Mayani, Héctor, Hernandez-Pando, Rogelio, Martinez-Maza, Otoniel, Huerta-Yepez, Sara, Bonavida, Benjamin, Vega, Mario I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609122/ https://www.ncbi.nlm.nih.gov/pubmed/26475474 http://dx.doi.org/10.1186/s12885-015-1778-8 |
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