Resampling to Address the Winner's Curse in Genetic Association Analysis of Time to Event

The “winner's curse” is a subtle and difficult problem in interpretation of genetic association, in which association estimates from large‐scale gene detection studies are larger in magnitude than those from subsequent replication studies. This is practically important because use of a biased e...

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Detalles Bibliográficos
Autores principales: Poirier, Julia G., Faye, Laura L., Dimitromanolakis, Apostolos, Paterson, Andrew D., Sun, Lei, Bull, Shelley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609263/
https://www.ncbi.nlm.nih.gov/pubmed/26411674
http://dx.doi.org/10.1002/gepi.21920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609263/
https://www.ncbi.nlm.nih.gov/pubmed/26411674
http://dx.doi.org/10.1002/gepi.21920

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