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The Expansion of CD25(high)IL-10(high)FoxP3(high) B Regulatory Cells Is in Association with SLE Disease Activity
B regulatory cells (Bregs) belong to a subgroup of activated B cells tasked with maintaining self-tolerance and preventing autoimmunity. While sharing similar regulatory mechanisms such as IL-10 dependency, they also defer in exhibiting their suppressive effects by expressing Fas-Ligand, TGF-beta, a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609458/ https://www.ncbi.nlm.nih.gov/pubmed/26504851 http://dx.doi.org/10.1155/2015/254245 |