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The Expansion of CD25(high)IL-10(high)FoxP3(high) B Regulatory Cells Is in Association with SLE Disease Activity

B regulatory cells (Bregs) belong to a subgroup of activated B cells tasked with maintaining self-tolerance and preventing autoimmunity. While sharing similar regulatory mechanisms such as IL-10 dependency, they also defer in exhibiting their suppressive effects by expressing Fas-Ligand, TGF-beta, a...

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Detalles Bibliográficos
Autores principales: Vadasz, Zahava, Peri, Regina, Eiza, Nasren, Slobodin, Gleb, Balbir-Gurman, Alexandra, Toubi, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609458/
https://www.ncbi.nlm.nih.gov/pubmed/26504851
http://dx.doi.org/10.1155/2015/254245