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Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation

Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous anta...

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Detalles Bibliográficos
Autores principales: He, Ting, Zhao, Liping, Zhang, Dongxia, Zhang, Qiong, Jia, Jiezhi, Hu, Jiongyu, Huang, Yuesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609513/
https://www.ncbi.nlm.nih.gov/pubmed/26504830
http://dx.doi.org/10.1155/2015/791825