Cargando…

Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation

Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous anta...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Ting, Zhao, Liping, Zhang, Dongxia, Zhang, Qiong, Jia, Jiezhi, Hu, Jiongyu, Huang, Yuesheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609513/ https://www.ncbi.nlm.nih.gov/pubmed/26504830 http://dx.doi.org/10.1155/2015/791825

Ejemplares similares

P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury
por: Li, Lingfei, et al.
Publicado: (2015)

High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway
por: Li, Lingfei, et al.
Publicado: (2019)

Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation
por: Zhang, Junhui, et al.
Publicado: (2019)

Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice
por: Li, Lingfei, et al.
Publicado: (2018)

Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction
por: Li, Lingfei, et al.
Publicado: (2019)

CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions
por: Zhang, Xingyue, et al.
Publicado: (2020)

Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation
por: Zhang, Junhui, et al.
Publicado: (2019)

Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury
por: Li, Lingfei, et al.
Publicado: (2019)

Hypoxia regulates CD9-mediated keratinocyte migration via the P38/MAPK pathway
por: Jiang, Xupin, et al.
Publicado: (2014)

Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement
por: Huang, Na, et al.
Publicado: (2018)

Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia
por: Feng, Yanhai, et al.
Publicado: (2023)

Correction: Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia
por: Feng, Yanhai, et al.
Publicado: (2023)

Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration
por: Zhang, Junhui, et al.
Publicado: (2019)

Author Correction: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration
por: Zhang, Junhui, et al.
Publicado: (2019)

H(+)/Cl(−) exchange transporter 7 promotes lysosomal acidification-mediated autophagy in mouse cardiomyocytes
por: Lin, Jiezhi, et al.
Publicado: (2021)

Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation
por: Chu, Ling-Yun, et al.
Publicado: (2016)

SPAK-p38 MAPK signal pathway modulates claudin-18 and barrier function of alveolar epithelium after hyperoxic exposure
por: Shen, Chih-Hao, et al.
Publicado: (2021)

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1
por: He, Yingli, et al.
Publicado: (2018)

Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes
por: Cui, Lin, et al.
Publicado: (2021)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
por: Zhang, Youwen, et al.
Publicado: (2010)

Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy
por: Li, Lingfei, et al.
Publicado: (2022)

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
por: Zhou, Mi, et al.
Publicado: (2020)

Involvement of p38 MAPK in Synaptic Function and Dysfunction
por: Falcicchia, Chiara, et al.
Publicado: (2020)

MAP4 as a New Candidate in Cardiovascular Disease
por: Li, Lingfei, et al.
Publicado: (2020)

Vitamin A deficiency compromises the barrier function of the retinal pigment epithelium
por: Moon, Jean, et al.
Publicado: (2023)

Relative Contribution of Different Mitochondrial Oxidative Phosphorylation Components to the Retinal Pigment Epithelium Barrier Function: Implications for RPE-Related Retinal Diseases
por: Guerra, Michael H., et al.
Publicado: (2021)

Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster
por: Batista, J.E.S., et al.
Publicado: (2016)

Pigment epithelium-derived factor alleviates endothelial injury by inhibiting Wnt/β-catenin pathway
por: Ma, Shouyuan, et al.
Publicado: (2017)

Qiangjing tablets repair of blood-testis barrier dysfunction in rats via regulating oxidative stress and p38 MAPK pathway
por: Li, Junjun, et al.
Publicado: (2022)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Histamine causes an imbalance between pro-angiogenic and anti-angiogenic factors in the retinal pigment epithelium of diabetic retina via H4 receptor/p38 MAPK axis
por: Lee, Byung Joo, et al.
Publicado: (2020)

Retinal Pigment Epithelium Derived Stem Cells
por: Hiscott, Paul, et al.
Publicado: (2009)

Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium
por: Ford, Knatokie M., et al.
Publicado: (2012)

Identification of a synergistic interaction between endothelial cells and retinal pigment epithelium
por: Spencer, Carrie, et al.
Publicado: (2017)

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium
por: Zhu, Zhe, et al.
Publicado: (2022)

p38β MAPK upregulates atrogin1/MAFbx by specific phosphorylation of C/EBPβ
por: Zhang, Guohua, et al.
Publicado: (2012)

Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC
por: Kanemura, Hoshimi, et al.
Publicado: (2013)

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)
por: Bullock, Jeanee, et al.
Publicado: (2021)

Molecular Mechanisms of Retinal Pigment Epithelium Dysfunction in Age-Related Macular Degeneration
por: Kim, Jongmin, et al.
Publicado: (2021)

Duration of streptozotocin-induced diabetes differentially affects p38-mitogen-activated protein kinase (MAPK) phosphorylation in renal and vascular dysfunction
por: Chen, Hongmei, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_dm9fgj60g3puv3kb1k6ttkglij