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Identification of Molecular Determinants of Primary and Metastatic Tumor Re-Initiation in Breast Cancer

Through in vivo selection of multiple ER-negative human breast cancer populations for enhanced tumor-forming capacity, we have derived sub-populations that generate tumors more efficiently than their parental populations at low cell numbers. Tumorigenic-enriched (TE) sub-populations displayed increa...

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Detalles Bibliográficos
Autores principales: Ross, Jason B., Huh, Doowon, Noble, Lisa B., Tavazoie, Sohail F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609531/
https://www.ncbi.nlm.nih.gov/pubmed/25866923
http://dx.doi.org/10.1038/ncb3148