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Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development

The zinc‐finger transcription factor GLI3 acts as a primary transducer of Sonic hedgehog (Shh) signaling in a context‐dependent combinatorial fashion. GLI3 participates in the patterning and growth of many organs, including the central nervous system (CNS) and limbs. Previously, we reported a subset...

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Detalles Bibliográficos
Autores principales: Anwar, Saneela, Minhas, Rashid, Ali, Shahid, Lambert, Nicholas, Kawakami, Yasuhiko, Elgar, Greg, Azam, Syed Sikandar, Abbasi, Amir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609622/
https://www.ncbi.nlm.nih.gov/pubmed/26464005
http://dx.doi.org/10.1111/dgd.12239