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Shear Stress Induces Differentiation of Endothelial Lineage Cells to Protect Neonatal Brain from Hypoxic-Ischemic Injury through NRP1 and VEGFR2 Signaling

Neonatal hypoxic-ischemic (HI) brain injuries disrupt the integrity of neurovascular structure and lead to lifelong neurological deficit. The devastating damage can be ameliorated by preserving the endothelial network, but the source for therapeutic cells is limited. We aim to evaluate the beneficia...

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Detalles Bibliográficos
Autores principales: Huang, Chia-Wei, Huang, Chao-Ching, Chen, Yuh-Ling, Fan, Shih-Chen, Hsueh, Yuan-Yu, Ho, Chien-Jung, Wu, Chia-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609802/
https://www.ncbi.nlm.nih.gov/pubmed/26509169
http://dx.doi.org/10.1155/2015/862485