Cargando…

Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy

Autophagy is an important homeostatic mechanism that eliminates long-lived proteins, protein aggregates and damaged organelles. Its dysregulation is involved in many neurodegenerative disorders. Autophagy is therefore a promising target for blunting neurodegeneration. We searched for novel autophagi...

Descripción completa

Detalles Bibliográficos
Autores principales: Moruno Manchon, Jose Felix, Uzor, Ndidi-Ese, Dabaghian, Yuri, Furr-Stimming, Erin E., Finkbeiner, Steven, Tsvetkov, Andrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609990/
https://www.ncbi.nlm.nih.gov/pubmed/26477494
http://dx.doi.org/10.1038/srep15213