Tamoxifen Augments the Innate Immune Function of Neutrophils Through Modulation of Intracellular Ceramide

Tamoxifen is a selective estrogen receptor modulator widely used for the treatment of breast cancer. In addition to its activity as an estrogen receptor agonist/antagonist, tamoxifen also modulates sphingolipid biosynthesis, which has been shown to play an important role in the regulation of neutrop...

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Detalles Bibliográficos
Autores principales: Corriden, Ross, Hollands, Andrew, Olson, Joshua, Derieux, Jaclyn, Lopez, Justine, Chang, John T., Gonzalez, David J., Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610010/
https://www.ncbi.nlm.nih.gov/pubmed/26458291
http://dx.doi.org/10.1038/ncomms9369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610010/
https://www.ncbi.nlm.nih.gov/pubmed/26458291
http://dx.doi.org/10.1038/ncomms9369

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