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Tamoxifen Augments the Innate Immune Function of Neutrophils Through Modulation of Intracellular Ceramide
Tamoxifen is a selective estrogen receptor modulator widely used for the treatment of breast cancer. In addition to its activity as an estrogen receptor agonist/antagonist, tamoxifen also modulates sphingolipid biosynthesis, which has been shown to play an important role in the regulation of neutrop...
Autores principales: | Corriden, Ross, Hollands, Andrew, Olson, Joshua, Derieux, Jaclyn, Lopez, Justine, Chang, John T., Gonzalez, David J., Nizet, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610010/ https://www.ncbi.nlm.nih.gov/pubmed/26458291 http://dx.doi.org/10.1038/ncomms9369 |
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