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Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and protecting neural tissue from damaging blood-borne agents. The barrier is characterized by endothelial tight junctions that limit passive paracellular diffusion of polar solutes and macromolecules from blood to brain. D...

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Detalles Bibliográficos
Autores principales: Keaney, James, Walsh, Dominic M., O’Malley, Tiernan, Hudson, Natalie, Crosbie, Darragh E., Loftus, Teresa, Sheehan, Florike, McDaid, Jacqueline, Humphries, Marian M., Callanan, John J., Brett, Francesca M., Farrell, Michael A., Humphries, Peter, Campbell, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610013/
https://www.ncbi.nlm.nih.gov/pubmed/26491725
http://dx.doi.org/10.1126/sciadv.1500472