Cargando…

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and protecting neural tissue from damaging blood-borne agents. The barrier is characterized by endothelial tight junctions that limit passive paracellular diffusion of polar solutes and macromolecules from blood to brain. D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keaney, James, Walsh, Dominic M., O’Malley, Tiernan, Hudson, Natalie, Crosbie, Darragh E., Loftus, Teresa, Sheehan, Florike, McDaid, Jacqueline, Humphries, Marian M., Callanan, John J., Brett, Francesca M., Farrell, Michael A., Humphries, Peter, Campbell, Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610013/ https://www.ncbi.nlm.nih.gov/pubmed/26491725 http://dx.doi.org/10.1126/sciadv.1500472

Ejemplares similares

Tricellulin Effect on Paracellular Water Transport
por: Ayala-Torres, Carlos, et al.
Publicado: (2019)

The Paracellular Pathway and Bile Formation
por: Boyer, James L., et al.
Publicado: (1979)

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity
por: Nicoll, Andrew J., et al.
Publicado: (2013)

Effect of Lactobacilli on Paracellular Permeability in the Gut
por: Ahrne, Siv, et al.
Publicado: (2011)

The Role of Paracellular Pathways in Isotonic Fluid Transport
por: Schultz, Stanley G.
Publicado: (1977)

Role of Stress on Driving the Intestinal Paracellular Permeability
por: Molotla-Torres, Daniel Efrain, et al.
Publicado: (2023)

The mammoth and the mouse : microhistory and morphology /
por: Egmond, Florike
Publicado: (1997)

Role of the septate junction in the regulation of paracellular transepithelial flow
Publicado: (1976)

Paracellular Absorption: A Bat Breaks the Mammal Paradigm
por: Caviedes-Vidal, Enrique, et al.
Publicado: (2008)

Claudin-2-dependent paracellular channels are dynamically gated
por: Weber, Christopher R, et al.
Publicado: (2015)

Effects of Osmolality on Paracellular Transport in MDCK II Cells
por: Tokuda, Shinsaku, et al.
Publicado: (2016)

Effect of Minoxidil on Trabecular Outflow via the Paracellular Pathway
por: Kang, Hyun Gu, et al.
Publicado: (2020)

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo
por: Hu, Neng-Wei, et al.
Publicado: (2014)

Improved outcomes in cystic fibrosis using modified Re-Education of Airway Clearance Technique (REACT) programme
por: Reamer, Courtney, et al.
Publicado: (2020)

The State of Autoregulation
por: Wolf, Stefan
Publicado: (2020)

Paracellular and transcellular migration of metastatic cells through the cerebral endothelium
por: Herman, Hildegard, et al.
Publicado: (2019)

Paracellular and Transcellular Leukocytes Diapedesis Are Divergent but Interconnected Evolutionary Events
por: Mickael, Michel-Edwar, et al.
Publicado: (2021)

The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
por: Markovic, Milica, et al.
Publicado: (2022)

Paracellular permeability and tight junction regulation in gut health and disease
por: Horowitz, Arie, et al.
Publicado: (2023)

Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm’s Canal Endothelia
por: Tam, Lawrence C. S., et al.
Publicado: (2017)

Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer’s Disease Disrupt Synaptic Plasticity
por: Hu, Neng-Wei, et al.
Publicado: (2018)

Transferring research to policy and practice: quo vadis?
por: McDaid, David
Publicado: (2009)

Regional and national experiences on bridging: a Western European perspective
por: McDaid, David
Publicado: (2009)

36. INVESTING IN RECOVERY – AN ECONOMIC AS WELL AS MORAL IMPERATIVE
por: McDaid, David
Publicado: (2018)

Viewpoint: Investing in strategies to support mental health recovery from the COVID-19 pandemic
por: McDaid, David
Publicado: (2021)

Role of the Paracellular Pathway in Isotonic Fluid Movement Across the Renal Tubule
por: Boulpaep, Emile L., et al.
Publicado: (1977)

Enhancing glucose flux into sweat by increasing paracellular permeability of the sweat gland
por: Jajack, Andrew, et al.
Publicado: (2018)

Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions
por: Konishi, Satoshi, et al.
Publicado: (2019)

A Framework of Paracellular Transport via Nanoparticles‐Induced Endothelial Leakiness
por: Lee, Myeongsang, et al.
Publicado: (2021)

Nanoscale segregation of channel and barrier claudins enables paracellular ion flux
por: Gonschior, Hannes, et al.
Publicado: (2022)

Computational study of ion permeation through claudin‐4 paracellular channels
por: Berselli, Alessandro, et al.
Publicado: (2022)

Candidate genes of the transcellular and paracellular calcium absorption pathways in the small intestine of laying hens
por: Gloux, A, et al.
Publicado: (2019)

A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid
por: Yang, Ting, et al.
Publicado: (2015)

Alcohol and drug use during unprotected anal intercourse among gay and bisexual men in Scotland: what are the implications for HIV prevention?
por: Li, Jessica, et al.
Publicado: (2014)

Risk of overestimating loss of cerebral autoregulation
por: Niño, María C., et al.
Publicado: (2022)

Deoxyhaemoglobin as a biomarker of cerebral autoregulation
por: Highton, D, et al.
Publicado: (2012)

Angulin-1 (LSR) Affects Paracellular Water Transport, However Only in Tight Epithelial Cells
por: Ayala-Torres, Carlos, et al.
Publicado: (2021)

Endothelial Domes Encapsulate Adherent Neutrophils and Minimize Increases in Vascular Permeability in Paracellular and Transcellular Emigration
por: Phillipson, Mia, et al.
Publicado: (2008)

Electrophysiology of flounder intestinal mucosa. I. Conductance properties of the cellular and paracellular pathways
Publicado: (1985)

Paracellular route is the major urate transport pathway across the blood‐placental barrier
por: Uehara, Ichiro, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1q64rkqkpeltrucpekob6i0gf2