5-Arylaminouracil Derivatives as Potential Dual-Action Agents

Several 5-aminouracil derivatives that have previously been shown to inhibit Mycobacterium tuberculosis growth at concentrations of 5–40 μg/mL are demonstrated to act also as noncompetitive non-nucleoside inhibitors of HIV-1 reverse transcriptase without causing toxicity in vitro (MT-4 cells) and ex...

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Detalles Bibliográficos
Autores principales: Matyugina, E. S., Novikov, M. S., Babkov, D. A., Valuev-Elliston, V. T., Vanpouille, C., Zicari, S., Corona, A., Tramontano, E., Margolis, L. B., Khandazhinskaya, A. L., Kochetkov, S. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610172/
https://www.ncbi.nlm.nih.gov/pubmed/26483967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610172/
https://www.ncbi.nlm.nih.gov/pubmed/26483967

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