Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells

The embryonic neural stem cell compartment is characterised by rapid proliferation from embryonic day (E)11 to E16.5, high endogenous DNA double-strand break (DSB) formation and sensitive activation of apoptosis. Here, we ask whether DSBs arise in the adult neural stem cell compartments, the sub-ven...

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Detalles Bibliográficos
Autores principales: Barazzuol, Lara, Rickett, Nicole, Ju, Limei, Jeggo, Penny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610209/
https://www.ncbi.nlm.nih.gov/pubmed/26303202
http://dx.doi.org/10.1242/jcs.171223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610209/
https://www.ncbi.nlm.nih.gov/pubmed/26303202
http://dx.doi.org/10.1242/jcs.171223

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