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Cytoophidium assembly reflects upregulation of IMPDH activity

Cytidine triphosphate synthase (CTPS) and inosine monophosphate dehydrogenase (IMPDH) (both of which have two isoforms) can form fiber-like subcellular structures termed ‘cytoophidia’ under certain circumstances in mammalian cells. Although it has been shown that filamentation of CTPS downregulates...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Chun, Lin, Wei-Cheng, Pai, Li-Mei, Lee, Hsuan-Shu, Wu, Shinn-Chih, Ding, Shih-Torng, Liu, Ji-Long, Sung, Li-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610212/
https://www.ncbi.nlm.nih.gov/pubmed/26303200
http://dx.doi.org/10.1242/jcs.175265