Vimentin is involved in regulation of mitochondrial motility and membrane potential by Rac1

In this study we show that binding of mitochondria to vimentin intermediate filaments (VIF) is regulated by GTPase Rac1. The activation of Rac1 leads to a redoubling of mitochondrial motility in murine fibroblasts. Using double-mutants Rac1(G12V, F37L) and Rac1(G12V, Y40H) that are capable to activa...

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Detalles Bibliográficos
Autores principales: Matveeva, Elena A., Venkova, Larisa S., Chernoivanenko, Ivan S., Minin, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610213/
https://www.ncbi.nlm.nih.gov/pubmed/26369929
http://dx.doi.org/10.1242/bio.011874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610213/
https://www.ncbi.nlm.nih.gov/pubmed/26369929
http://dx.doi.org/10.1242/bio.011874

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