The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster

The lysosomal enzyme receptor protein (LERP) of Drosophila melanogaster is the ortholog of the mammalian cation-independent mannose 6-phosphate (Man 6-P) receptor, which mediates trafficking of newly synthesized lysosomal acid hydrolases to lysosomes. However, flies lack the enzymes necessary to mak...

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Detalles Bibliográficos
Autores principales: Hasanagic, Medina, van Meel, Eline, Luan, Shan, Aurora, Rajeev, Kornfeld, Stuart, Eissenberg, Joel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610224/
https://www.ncbi.nlm.nih.gov/pubmed/26405051
http://dx.doi.org/10.1242/bio.013334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610224/
https://www.ncbi.nlm.nih.gov/pubmed/26405051
http://dx.doi.org/10.1242/bio.013334

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