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Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy

Cancer initiation and maintenance of the transformed cell state depend on altered cellular signaling and aberrant activities of transcription factors (TFs) that drive pathological gene expression in response to cooperating genetic lesions. Deciphering the roles of interacting TFs is therefore centra...

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Detalles Bibliográficos
Autores principales: Külshammer, Eva, Mundorf, Juliane, Kilinc, Merve, Frommolt, Peter, Wagle, Prerana, Uhlirova, Mirka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610234/
https://www.ncbi.nlm.nih.gov/pubmed/26398940
http://dx.doi.org/10.1242/dmm.020719