Systematic VCP-UBXD Adaptor Network Proteomics Identifies a Role for UBXN10 in Regulating Ciliogenesis

The AAA-ATPase VCP (also known as p97 or CDC48) uses ATP hydrolysis to “segregate” ubiquitinated proteins from their binding partners. VCP acts via UBX-domain containing adaptors that provide target specificity, but targets and functions of UBXD proteins remain poorly understood. Through systematic...

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Detalles Bibliográficos
Autores principales: Raman, Malavika, Sergeev, Mikhail, Garnaas, Maija, Lydeard, John R., Huttlin, Edward L., Goessling, Wolfram, Shah, Jagesh V., Harper, J. Wade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610257/
https://www.ncbi.nlm.nih.gov/pubmed/26389662
http://dx.doi.org/10.1038/ncb3238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610257/
https://www.ncbi.nlm.nih.gov/pubmed/26389662
http://dx.doi.org/10.1038/ncb3238

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