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Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals

BACKGROUND: The development of new drugs for the treatment of diabetes mellitus (DM) is critically important. Insulin resistance (IR) is one of the main problems associated with type-2 DM (T2DM) seen in clinics. GW0742, a selective peroxisome proliferator-activated receptor (PPAR)-δ agonist, has bee...

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Detalles Bibliográficos
Autores principales: Niu, Ho-Shan, Ku, Po-Ming, Niu, Chiang-Shan, Cheng, Juei-Tang, Lee, Kung-Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610778/
https://www.ncbi.nlm.nih.gov/pubmed/26508837
http://dx.doi.org/10.2147/DDDT.S95045