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Cyclosporin A in Membrane Lipids Environment: Implications for Antimalarial Activity of the Drug—The Langmuir Monolayer Studies

Cyclosporin A (CsA), a hydrophobic cyclic peptide produced by the fungus Tolypocladium inflatum, is well known for its high efficiency as an immunosuppressor for transplanted organs and anti-inflammatory properties; however, it is also active as antiparasitic (antimalarial) drug. Antimalarial mechan...

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Detalles Bibliográficos
Autores principales: Dynarowicz-Łątka, Patrycja, Wnętrzak, Anita, Makyła-Juzak, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611017/
https://www.ncbi.nlm.nih.gov/pubmed/26077844
http://dx.doi.org/10.1007/s00232-015-9814-9