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Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection

Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In a large series of Malawian children hospitalized...

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Detalles Bibliográficos
Autores principales: Hochman, Sarah E., Madaline, Theresa F., Wassmer, Samuel C., Mbale, Emmie, Choi, Namjong, Seydel, Karl B., Whitten, Richard O., Varughese, Julie, Grau, Georges E. R., Kamiza, Steve, Molyneux, Malcolm E., Taylor, Terrie E., Lee, Sunhee, Milner, Danny A., Kim, Kami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611030/
https://www.ncbi.nlm.nih.gov/pubmed/26396242
http://dx.doi.org/10.1128/mBio.01390-15