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Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection
Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In a large series of Malawian children hospitalized...
Autores principales: | Hochman, Sarah E., Madaline, Theresa F., Wassmer, Samuel C., Mbale, Emmie, Choi, Namjong, Seydel, Karl B., Whitten, Richard O., Varughese, Julie, Grau, Georges E. R., Kamiza, Steve, Molyneux, Malcolm E., Taylor, Terrie E., Lee, Sunhee, Milner, Danny A., Kim, Kami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611030/ https://www.ncbi.nlm.nih.gov/pubmed/26396242 http://dx.doi.org/10.1128/mBio.01390-15 |
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