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Inducing Oncoprotein Degradation to Improve Targeted Cancer Therapy()
Over the past decade, inhibition of the kinase activities of oncogenic proteins using small molecules and antibodies has been a mainstay of our anticancer drug development effort, resulting in several Food and Drug Administration–approved cancer therapies. The clinical effectiveness of kinase-target...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611070/ https://www.ncbi.nlm.nih.gov/pubmed/26476077 http://dx.doi.org/10.1016/j.neo.2015.08.008 |