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SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein()

Nucleophosmin-anaplastic lymphoma kinase–expressing (NPM-ALK(+)) T-cell lymphoma is an aggressive form of cancer that commonly affects children and adolescents. The expression of NPM-ALK chimeric oncogene results from the chromosomal translocation t(2;5)(p23;q35) that causes the fusion of the ALK an...

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Detalles Bibliográficos
Autores principales: Vishwamitra, Deeksha, Curry, Choladda V., Shi, Ping, Alkan, Serhan, Amin, Hesham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611074/
https://www.ncbi.nlm.nih.gov/pubmed/26476082
http://dx.doi.org/10.1016/j.neo.2015.09.005