Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells()

Lysophosphatidic acid (LPA), a blood-borne lipid mediator, is present in elevated concentrations in ascites of ovarian cancer patients and other malignant effusions. LPA is a potent mitogen in cancer cells. The mechanism linking LPA signal to cancer cell proliferation is not well understood. Little...

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Detalles Bibliográficos
Autores principales: Mukherjee, Abir, Ma, Yibao, Yuan, Fang, Gong, Yongling, Fang, Zhenyu, Mohamed, Esraa M., Berrios, Erika, Shao, Huanjie, Fang, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611075/
https://www.ncbi.nlm.nih.gov/pubmed/26476080
http://dx.doi.org/10.1016/j.neo.2015.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611075/
https://www.ncbi.nlm.nih.gov/pubmed/26476080
http://dx.doi.org/10.1016/j.neo.2015.09.003

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