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Insights into the molecular mechanism of allostery in Hsp70s

Hsp70s chaperone an amazing number and variety of cellular protein folding processes. Key to their versatility is the recognition of a short degenerate sequence motif, present in practically all polypeptides, and a bidirectional allosteric intramolecular regulation mechanism linking their N-terminal...

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Detalles Bibliográficos
Autores principales: Mayer, Matthias P., Kityk, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611139/
https://www.ncbi.nlm.nih.gov/pubmed/26539440
http://dx.doi.org/10.3389/fmolb.2015.00058