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Integrins are Mechanosensors That Modulate Human Eosinophil Activation

Eosinophil migration to the lung is primarily regulated by the eosinophil-selective family of eotaxin chemokines, which mobilize intracellular calcium (Ca(2+)) and orchestrate myriad changes in cell structure and function. Eosinophil function is also known to be flow-dependent, although the molecula...

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Detalles Bibliográficos
Autores principales: Ahmadzai, Mustafa, Small, Mike, Sehmi, Roma, Gauvreau, Gail, Janssen, Luke J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611147/
https://www.ncbi.nlm.nih.gov/pubmed/26539194
http://dx.doi.org/10.3389/fimmu.2015.00525