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The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humans
Recent phylogenetic analyses indicate that RNA virus populations carry a significant deleterious mutation load. This mutation load has the potential to shape patterns of adaptive evolution via genetic linkage to beneficial mutations. Here, we examine the effect of deleterious mutations on patterns o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611170/ https://www.ncbi.nlm.nih.gov/pubmed/26371556 http://dx.doi.org/10.7554/eLife.07361 |