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FADD regulates thymocyte development at the β-selection checkpoint by modulating Notch signaling

Non-apoptotic functions of Fas-associated protein with death domain (FADD) have been implicated in T lineage lymphocytes, but the nature of FADD-dependent non-apoptotic mechanism in early T-cell development has not been completely elucidated. In this study, we show that tissue-specific deletion of F...

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Detalles Bibliográficos
Autores principales: Zhang, X, Dong, X, Wang, H, Li, J, Yang, B, Zhang, J, Hua, Z-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611708/
https://www.ncbi.nlm.nih.gov/pubmed/24901044
http://dx.doi.org/10.1038/cddis.2014.198