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Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells

The retinoblastoma protein (RB) is essential for normal cell cycle control. RB function depends, at least in part, on interactions with the E2F family of DNA-binding transcription factors (E2Fs). To study the role of RB in the adult testis, a Sertoli cell (SC)-specific Rb knockout mouse line (SC-RbK...

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Detalles Bibliográficos
Autores principales: Rotgers, E, Rivero-Müller, A, Nurmio, M, Parvinen, M, Guillou, F, Huhtaniemi, I, Kotaja, N, Bourguiba-Hachemi, S, Toppari, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611710/
https://www.ncbi.nlm.nih.gov/pubmed/24901045
http://dx.doi.org/10.1038/cddis.2014.232