Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis

Chemotherapy resistance of tumor cells is a big challenge. Adaption to hypoxia is an essential cellular response that is controlled by the master oxygen-sensitive transcription factor HIF1 (hypoxia-inducible factor 1). The mechanism by which tumor cells acquire resistance to chemotherapy under hypox...

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Detalles Bibliográficos
Autores principales: Zhang, D, Shi, Z, Li, M, Mi, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611715/
https://www.ncbi.nlm.nih.gov/pubmed/24967963
http://dx.doi.org/10.1038/cddis.2014.240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611715/
https://www.ncbi.nlm.nih.gov/pubmed/24967963
http://dx.doi.org/10.1038/cddis.2014.240

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