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Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis
Chemotherapy resistance of tumor cells is a big challenge. Adaption to hypoxia is an essential cellular response that is controlled by the master oxygen-sensitive transcription factor HIF1 (hypoxia-inducible factor 1). The mechanism by which tumor cells acquire resistance to chemotherapy under hypox...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611715/ https://www.ncbi.nlm.nih.gov/pubmed/24967963 http://dx.doi.org/10.1038/cddis.2014.240 |