Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways

Acetylation homeostasis is thought to play a role in amyotrophic lateral sclerosis, and treatment with inhibitors of histone deacetylases has been considered a potential and attractive therapeutic approach, despite the lack of a thorough study of this class of proteins. In this study, we have consid...

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Detalles Bibliográficos
Autores principales: Valle, C, Salvatori, I, Gerbino, V, Rossi, S, Palamiuc, L, René, F, Carrì, M T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611720/
https://www.ncbi.nlm.nih.gov/pubmed/24946089
http://dx.doi.org/10.1038/cddis.2014.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611720/
https://www.ncbi.nlm.nih.gov/pubmed/24946089
http://dx.doi.org/10.1038/cddis.2014.247

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