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DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease

In the brain, programmed cell death (PCD) serves to adjust the numbers of the different types of neurons during development, and its pathological reactivation in the adult leads to neurodegeneration. Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) is a pleiotropic kinase i...

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Detalles Bibliográficos
Autores principales: Barallobre, M J, Perier, C, Bové, J, Laguna, A, Delabar, J M, Vila, M, Arbonés, M L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611726/
https://www.ncbi.nlm.nih.gov/pubmed/24922073
http://dx.doi.org/10.1038/cddis.2014.253