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DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease
In the brain, programmed cell death (PCD) serves to adjust the numbers of the different types of neurons during development, and its pathological reactivation in the adult leads to neurodegeneration. Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) is a pleiotropic kinase i...
Autores principales: | Barallobre, M J, Perier, C, Bové, J, Laguna, A, Delabar, J M, Vila, M, Arbonés, M L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611726/ https://www.ncbi.nlm.nih.gov/pubmed/24922073 http://dx.doi.org/10.1038/cddis.2014.253 |
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