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Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death

Acute lung injury (ALI) is characterized by pulmonary endothelial and epithelial cell damage, and loss of the alveolar–capillary barrier. We have previously shown that P2X7 receptor (P2X7R), a cell death receptor, is specifically expressed in alveolar epithelial type I cells (AEC I). In this study,...

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Detalles Bibliográficos
Autores principales: Guo, Y, Mishra, A, Weng, T, Chintagari, N R, Wang, Y, Zhao, C, Huang, C, Liu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611727/
https://www.ncbi.nlm.nih.gov/pubmed/24922070
http://dx.doi.org/10.1038/cddis.2014.254