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Activation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal gland

The pathogenesis of immune-mediated lacrimal gland (LG) dysfunction in Sjögren's syndrome has been thoroughly studied. However, the majority of dry eye (DE) is not related to Sjögren type, and its pathophysiology remains unclear. The purpose of this study was to determine and investigate the pr...

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Detalles Bibliográficos
Autores principales: Seo, Y, Ji, Y W, Lee, S M, Shim, J, Noh, H, Yeo, A, Park, C, Park, M S, Chang, E J, Lee, H K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611733/
https://www.ncbi.nlm.nih.gov/pubmed/24967971
http://dx.doi.org/10.1038/cddis.2014.260