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Vaccination Programs for Endemic Infections: Modelling Real versus Apparent Impacts of Vaccine and Infection Characteristics

Vaccine effect, as measured in clinical trials, may not accurately reflect population-level impact. Furthermore, little is known about how sensitive apparent or real vaccine impacts are to factors such as the risk of re-infection or the mechanism of protection. We present a dynamic compartmental mod...

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Detalles Bibliográficos
Autores principales: Ragonnet, Romain, Trauer, James M., Denholm, Justin T., Geard, Nicholas L., Hellard, Margaret, McBryde, Emma S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611864/
https://www.ncbi.nlm.nih.gov/pubmed/26482413
http://dx.doi.org/10.1038/srep15468