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TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response

Leukocyte transendothelial migration (TEM) is a tightly regulated, multistep process that is critical to the inflammatory response. A transient increase in endothelial cytosolic free calcium ion concentration (↑[Ca(2+)](i)) is required for TEM. However, the mechanism by which endothelial ↑[Ca(2+)](i...

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Detalles Bibliográficos
Autores principales: Weber, Evan W., Han, Fei, Tauseef, Mohammad, Birnbaumer, Lutz, Mehta, Dolly, Muller, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612081/
https://www.ncbi.nlm.nih.gov/pubmed/26392222
http://dx.doi.org/10.1084/jem.20150353