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TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
Leukocyte transendothelial migration (TEM) is a tightly regulated, multistep process that is critical to the inflammatory response. A transient increase in endothelial cytosolic free calcium ion concentration (↑[Ca(2+)](i)) is required for TEM. However, the mechanism by which endothelial ↑[Ca(2+)](i...
Autores principales: | Weber, Evan W., Han, Fei, Tauseef, Mohammad, Birnbaumer, Lutz, Mehta, Dolly, Muller, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612081/ https://www.ncbi.nlm.nih.gov/pubmed/26392222 http://dx.doi.org/10.1084/jem.20150353 |
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