Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis

Bone surfaces attract hematopoietic and nonhematopoietic cells, such as osteoclasts (OCs) and osteoblasts (OBs), and are targeted by bone metastatic cancers. However, the mechanisms guiding cells toward bone surfaces are essentially unknown. Here, we show that the Gαi protein–coupled receptor (GPCR)...

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Detalles Bibliográficos
Autores principales: Nevius, Erin, Pinho, Flavia, Dhodapkar, Meera, Jin, Huiyan, Nadrah, Kristina, Horowitz, Mark C., Kikuta, Junichi, Ishii, Masaru, Pereira, João P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612084/
https://www.ncbi.nlm.nih.gov/pubmed/26438360
http://dx.doi.org/10.1084/jem.20150088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612084/
https://www.ncbi.nlm.nih.gov/pubmed/26438360
http://dx.doi.org/10.1084/jem.20150088

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