Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways

Pancreatic ductal adenocarcinoma is one of the most aggressive malignancies, characterized by the local invasion into surrounding tissues and early metastasis to distant organs. Oncogenic mutations of the K-RAS gene occur in more than 90% of human pancreatic cancers. The goal of this study was to in...

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Detalles Bibliográficos
Autores principales: Padavano, Julianna, Henkhaus, Rebecca S, Chen, Hwudaurw, Skovan, Bethany A, Cui, Haiyan, Ignatenko, Natalia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612127/
https://www.ncbi.nlm.nih.gov/pubmed/26512205
http://dx.doi.org/10.4137/CGM.S29407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612127/
https://www.ncbi.nlm.nih.gov/pubmed/26512205
http://dx.doi.org/10.4137/CGM.S29407

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