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No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study

Objective: Hypoxia Inducible Factor‐1 (HIF‐1) is an important transcription factor that stimulates tumour growth and metastases via several pathways, including angiogenesis and altered metabolism. Activation of HIF‐1 depends on the levels of its α‐subunit, which increase during hypoxia. Recent studi...

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Detalles Bibliográficos
Autores principales: Vleugel, Marije M., Bos, Reinhard, Buerger, Horst, van der Groep, Petra, Saramäki, Outi R., Visakorpi, Tapio, van der Wall, Elsken, van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612258/
https://www.ncbi.nlm.nih.gov/pubmed/15623945
http://dx.doi.org/10.1155/2004/532413